Apoptosis-enhanced ferroptosis therapy of pancreatic carcinoma through PAMAM dendrimer-iron(III) complex-based plasmid delivery
Wenjing Ma, Yue Gao, Zhijun Ouyang, Yu Fan, Hongwei Yu, Mengsi Zhan, Han Wang, Xiangyang Shi, Mingwu Shen
Topics & Concepts
DendrimerApoptosisChemistryReactive oxygen speciesGenetic enhancementGene deliveryCancer researchBiophysicsNanomedicineDownregulation and upregulationChelationTumor microenvironmentNanotechnologyNanoparticleMaterials scienceBiochemistryGeneBiologyTumor cellsOrganic chemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryEpigenetics and DNA Methylation