Recent knowledge in phages, phage-encoded endolysin, and phage encapsulation against foodborne pathogens
Jie Yang, Xiaolong Zhu, Xingfeng Xu, Qingjie Sun
Abstract
The use of antibiotics had reached a plateau due to antibiotic resistance, overuse, and residue. Bacteriophages have recently attracted considerable attention as alternative biocontrol agents. Here, we provide an up-to-date overview of phage applications in the food industry. We reviewed recently reported phages against ten typical foodborne pathogens, studies of competitive phage-encoded endolysins, and the primary outcomes of phage encapsulation in food packaging and pathogen detection. Furthermore, we identified existing barriers that still need to be addressed and proposed potential solutions to overcome these obstacles in the future.
Topics & Concepts
LysinBacteriophagePhage therapyBiologyAntibiotic resistanceMicrobiologyFoodborne pathogenBiotechnologyFood productsPathogenFood safetyAntibioticsBacteriaFood scienceGeneticsEscherichia coliGeneListeria monocytogenesBacteriophages and microbial interactionsMicrobial infections and disease researchViral gastroenteritis research and epidemiology