Synthesis and screening of novel 4-N-heterocyclic-2-aryl-6,7,8-trimethoxyquinazolines as antiproliferative and tubulin polymerization inhibitors
Ashish Ranjan Dwivedi, Suraj Singh Rawat, Vijay Kumar, Naveen Kumar, Piyush Anand, Ravi Prakash Yadav, Somesh Baranwal, Amit Prasad, Vinod Kumar
Topics & Concepts
ChemistryHeLaTubulinArylStereochemistryApoptosisIC50Cell cultureMicrotubuleCellIn vitroBiochemistryOrganic chemistryBiologyAlkylGeneticsCell biologySynthesis and biological activityQuinazolinone synthesis and applicationsSynthesis and Characterization of Heterocyclic Compounds