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Luteolin and its analog luteolin-7-methylether from Leonurus japonicus Houtt suppress aromatase-mediated estrogen biosynthesis to alleviate polycystic ovary syndrome by the inhibition of tumor progression locus 2

Xiaoke Shi, Ting Peng, Bahtigul Azimova, Xiaoli Li, Shanshan Li, Dongyi Cao, Naijie Fu, Guolin Zhang, Wei‐Lie Xiao, Fei Wang

2024Journal of Ethnopharmacology15 citationsDOI

Topics & Concepts

LuteolinPolycystic ovaryAromataseMAPK/ERK pathwayCREBPharmacologyBiologyPI3K/AKT/mTOR pathwayEstrogenEndocrinologySignal transductionInternal medicineCancer researchMedicineTranscription factorCell biologyFlavonoidBiochemistryInsulinInsulin resistanceGeneCancerBreast cancerAntioxidantMenopause: Health Impacts and TreatmentsEstrogen and related hormone effectsOvarian cancer diagnosis and treatment
Luteolin and its analog luteolin-7-methylether from Leonurus japonicus Houtt suppress aromatase-mediated estrogen biosynthesis to alleviate polycystic ovary syndrome by the inhibition of tumor progression locus 2 | Litcius