G1/S arrest: a key mechanism of cellular aging and replicative senescence
Xiangdong Li, Xin Yan, Qi Chen, Sui Mai
Topics & Concepts
SenescenceCell biologyBiologyDNA damageCell cycleCell divisionDNA replicationCellMechanism (biology)Cell cycle checkpointCell growthDNA synthesisDNAGeneticsDNA repairCell cycle progressionTelomerePhenotypeTransition (genetics)Signal transductionGenome instabilityCell cultureKinaseTelomeres, Telomerase, and SenescenceCancer-related Molecular PathwaysDNA Repair Mechanisms