Povidone Iodine: Properties, Mechanisms of Action, and Role in Infection Control and <i>Staphylococcus aureus</i> Decolonization
Didier Lepelletier, Jean Maillard, Bruno Pozzetto, Anne Simon
Abstract
Nasal decolonization is an integral part of the strategies used to control and prevent the spread of methicillin-resistant Staphylococcus aureus (MRSA) infections. The two most commonly used agents for decolonization are intranasal mupirocin 2% ointment and chlorhexidine wash, but the increasing emergence of resistance and treatment failure has underscored the need for alternative therapies. This article discusses povidone iodine (PVP-I) as an alternative decolonization agent and is based on literature reviewed during an expert’s workshop on resistance and MRSA decolonization.
Topics & Concepts
Staphylococcus aureusIodineMicrobiologyStaphylococcal infectionsMedicineAction (physics)BiologyChemistryBacteriaGeneticsQuantum mechanicsPhysicsOrganic chemistryAntimicrobial Resistance in StaphylococcusAntibiotics Pharmacokinetics and EfficacyOcular Infections and Treatments