Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2
Wei Huang, Yitao Xing, Lile Zhu, Jinsheng Zhuo, Min Cai
Topics & Concepts
SorafenibAngiogenesisVascular endothelial growth factorIn vivoCancer researchPharmacologyMetastasisColloidal goldUmbilical veinMaterials scienceBiologyIn vitroMedicineHepatocellular carcinomaInternal medicineBiochemistryCancerNanotechnologyNanoparticleVEGF receptorsBiotechnologyCancer Mechanisms and TherapyNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics