DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells
Raghav Ramabadran, Jarey H. Wang, Jaime M. Reyes, Anna Guzman, Sinjini Gupta, Carina Rosas, Lorenzo Brunetti, Michael C. Gundry, Ayala Tovy, Hali Long, Tianpeng Gu, Sean M. Cullen, Siddhartha Tyagi, Danielle Rux, Ji‐Eun Kim, Steven M. Kornblau, Michael Kyba, Fabio Stossi, Rachel E. Rau, Koichi Takahashi, Thomas F. Westbrook, Margaret A. Goodell
Topics & Concepts
SpliceosomeStem cellRNA splicingBiologyCell biologyHaematopoiesisEmbryonic stem cellCellular differentiationEpigeneticsDNA methylationRNAGeneticsGene expressionGeneEpigenetics and DNA MethylationRNA modifications and cancerAcute Myeloid Leukemia Research