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Clinical Approaches for the Management of Skin Cancer: A Review of Current Progress in Diagnosis, Treatment, and Prognosis for Patients with Melanoma

Christopher M. O Connor, Quinton L Carr, Alisa Sweazy, Kelly M. McMasters, Hongying Hao

2025Cancers19 citationsDOIOpen Access PDF

Abstract

Melanoma represents a significant public health challenge due to its increasing incidence and potential for metastasis. This review will explore the current clinical approaches to the management of melanoma, focusing on advancements in diagnosis, treatment, and prognosis. Methods for early detection and accurate staging have been enhanced by new diagnostic strategies. Treatment modalities have expanded beyond traditional surgical excision to include targeted therapy and immunotherapy. Prognostic assessment has benefited from the development of novel biomarkers and genetic profiling. This review will highlight the progress made in the multidisciplinary management of melanoma, underscoring the importance of continuous research to improve patient outcomes.

Topics & Concepts

MedicineMelanomaMultidisciplinary approachIntensive care medicineModalitiesImmunotherapySkin cancerClinical PracticeTargeted therapyMetastasisCancerInternal medicinePhysical therapyCancer researchSocial scienceSociologyCutaneous Melanoma Detection and ManagementMelanoma and MAPK PathwaysCAR-T cell therapy research
Clinical Approaches for the Management of Skin Cancer: A Review of Current Progress in Diagnosis, Treatment, and Prognosis for Patients with Melanoma | Litcius