Post-ERCP Pancreatitis: Prevention, Diagnosis and Management
Oscar Cahyadi, Nadeem Tehami, Enrique de‐Madaria, Keith Siau
Abstract
Endoscopic retrograde cholangiopancreatography (ERCP) carries a post-ERCP pancreatitis (PEP) rate of 2-10%, which could be as high as 30-50% in high-risk cases. PEP is severe in up to 5% of cases, with potential for life-threatening complications, including multi-organ failure, peripancreatic fluid collections, and death in up to 1% of cases. The risk of PEP is potentially predictable and may be modified with pharmacological measures and endoscopist technique. This review covers the definition, epidemiology and risk factors for PEP, with a focus on the latest evidence-based medical and endoscopic strategies to prevent and manage PEP.
Topics & Concepts
Endoscopic retrograde cholangiopancreatographyMedicinePancreatitisEpidemiologyGeneral surgeryIntensive care medicineInternal medicineGallbladder and Bile Duct DisordersPediatric Hepatobiliary Diseases and TreatmentsEsophageal and GI Pathology