Studying the impact of geometrical and cellular cues on myogenesis with a skeletal muscle-on-chip
M.-L. Nguyen, Noam Demri, Б. А. Лапин, Fahima Di Federico, Giacomo Gropplero, Fanny Cayrac, Katharina Hennig, Edgar R. Gomes, Claire Wilhelm, William Roman, Stéphanie Descroix
Abstract
In the skeletal muscle tissue, cells are organized following an anisotropic architecture, which is both required during myogenesis when muscle precursor cells fuse to generate myotubes and for its contractile function.
Topics & Concepts
MyogenesisSkeletal muscleMyocyteCell biologyFunction (biology)AnatomyBiologyChemistry3D Printing in Biomedical ResearchNeuroscience and Neural EngineeringMuscle Physiology and Disorders