Phenolamide extract of apricot bee pollen alleviates glucolipid metabolic disorders and modulates the gut microbiota and metabolites in high-fat diet-induced obese mice
Xingxing Zhang, Xin Wu, Gengsheng Xiao, Gongliang Liu, Hao Dong, Rui Liu, Qun Lu
Abstract
. Metabolomic analysis revealed that PAE could regulate the levels of metabolites, including bile acids, phosphatidyl choline (PC), lysophosphatidylcholine (lysoPC), lysophosphatidylethanolamine (lysoPE) and tyrosine. This is the first study finding that PAE can regulate glucolipid metabolism and modulate the gut microbiota and metabolites in HFD-induced obese mice, and the results indicate that PAE can be used as a functional dietary supplement to alleviate HFD-induced obesity.
Topics & Concepts
Gut floraBee pollenDiet-induced obeseLipid metabolismBiologyFirmicutesBacteroidetesEndocrinologyFood scienceChemistryInternal medicineObesityBiochemistryInsulin resistanceBotanyMedicinePollenGene16S ribosomal RNAMetabolomics and Mass Spectrometry StudiesGut microbiota and healthDiet and metabolism studies