Applying high throughput and comprehensive immunoinformatics approaches to design a trivalent subunit vaccine for induction of immune response against emerging human coronaviruses SARS-CoV, MERS-CoV and SARS-CoV-2
Abolfazl Rahmani, Masoud Baee, Kiarash Saleki, Saead Moradi, Hamid Reza Nouri
Abstract
cloning guaranteed increased expression. In summary, investigations demonstrated that this next-generation approach might provide a new horizon for the development of a highly immunogenic vaccine against SARS-CoV, MERS-CoV, and SARS-CoV-2.Communicated by Ramaswamy H. Sarma.
Topics & Concepts
EpitopeBiologyVirologyImmune systemAdjuvantAntigenIn silicoCoronavirusImmunogenicityComputational biologyImmunologyGeneticsGeneMedicineInfectious disease (medical specialty)Coronavirus disease 2019 (COVID-19)PathologyDiseasevaccines and immunoinformatics approachesImmunotherapy and Immune ResponsesMonoclonal and Polyclonal Antibodies Research