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Photo-on-Demand Base-Catalyzed Phosgenation Reactions with Chloroform: Synthesis of Arylcarbonate and Halocarbonate Esters

Yuka Hashimoto, Sasuga Hosokawa, Fengying Liang, Yuto Suzuki, Namin Dai, Gegen Tana, Kazuo Eda, Toshifumi Kakiuchi, Takashi Okazoe, H. Harada, Akihiko Tsuda

2021The Journal of Organic Chemistry20 citationsDOI

Abstract

Carbonate esters are utilized as solvents and reagents for C1 building blocks in organic synthesis. This study reports a novel photo-on-demand in situ synthesis of carbonate esters with CHCl3 solutions containing a mixture of an aromatic or haloalkyl alcohol having relatively high acidity, and an organic base. We found that the acid–base interaction of the alcohol and base in the CHCl3 solution plays a key role in enabling the photochemical reaction. This reaction allows practical syntheses of diphenyl carbonate derivatives, haloalkyl carbonates, and polycarbonates, which are important chemicals and materials in industry.

Topics & Concepts

ChemistryChloroformReagentBase (topology)CarbonateCatalysisAlcoholOrganic chemistryOrganic baseOrganic synthesisPropylene carbonateCombinatorial chemistryMathematicsElectrochemistryPhysical chemistryElectrodeMathematical analysisCarbon dioxide utilization in catalysisChemical Synthesis and ReactionsSulfur-Based Synthesis Techniques
Photo-on-Demand Base-Catalyzed Phosgenation Reactions with Chloroform: Synthesis of Arylcarbonate and Halocarbonate Esters | Litcius