Influence of the reducing-end anomeric configuration of the Man<sub>9</sub> epitope on DC-SIGN recognition
Noelia de la Cruz, Javier Ramos‐Soriano, José J. Reina, José L. de Paz, Michel Thépaut, Franck Fieschi, Ana Sousa‐Herves, Javier Rojo
Abstract
alpha epitope may be deployed as ligand for DC-SIGN in both in vitro and in vivo biological assays.
Topics & Concepts
DC-SIGNEpitopeMannoseMannose receptorIn silicoChemistryGlycoproteinBiologyBiochemistryComputational biologyIn vitroGeneticsDendritic cellAntibodyAntigenGeneMacrophageGlycosylation and Glycoproteins ResearchImmunotherapy and Immune ResponsesHIV Research and Treatment