Directly targeting glutathione peroxidase 4 may be more effective than disrupting glutathione on ferroptosis-based cancer therapy
Yunpeng Wei, Huanhuan Lv, Atik Badshah Shaikh, Wei Han, Hongjie Hou, Zhihao Zhang, Shenghang Wang, Peng Shang
Topics & Concepts
GPX4Cancer cellGlutathioneIn vivoCancerCancer researchGlutathione peroxidaseChemistryBiologyMedicineBiochemistryInternal medicineGeneticsEnzymeFerroptosis and cancer prognosisEpigenetics and DNA MethylationImmune cells in cancer