Litcius/Paper detail

Directly targeting glutathione peroxidase 4 may be more effective than disrupting glutathione on ferroptosis-based cancer therapy

Yunpeng Wei, Huanhuan Lv, Atik Badshah Shaikh, Wei Han, Hongjie Hou, Zhihao Zhang, Shenghang Wang, Peng Shang

2020Biochimica et Biophysica Acta (BBA) - General Subjects74 citationsDOI

Topics & Concepts

GPX4Cancer cellGlutathioneIn vivoCancerCancer researchGlutathione peroxidaseChemistryBiologyMedicineBiochemistryInternal medicineGeneticsEnzymeFerroptosis and cancer prognosisEpigenetics and DNA MethylationImmune cells in cancer