PI3Kαδ Inhibitor Combined With Radiation Enhances the Antitumor Immune Effect of Anti-PD1 in a Syngeneic Murine Triple-Negative Breast Cancer Model
Won Ick Chang, Min Guk Han, Mi Hyun Kang, Ji Min Park, Eric Eunshik Kim, Junhyung Bae, Soyeon Ahn, In Ah Kim
Topics & Concepts
Tumor microenvironmentImmune systemCancer researchImmune checkpointCD8Cytotoxic T cellTriple-negative breast cancerT cellPI3K/AKT/mTOR pathwayBlockadeMedicineImmunotherapyBreast cancerImmunologyCancerBiologyInternal medicineReceptorApoptosisBiochemistryIn vitroCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCancer Research and Treatments