<i>cotH</i> Genes Are Necessary for Normal Spore Formation and Virulence in <i>Mucor lusitanicus</i>
Csilla Szebenyi, Yiyou Gu, Teclegiorgis Gebremariam, Sándor Kocsubé́, Sándor Kiss-Vetráb, Olivér Jáger, Roland Patai, Krisztina Spisák, Rita Sinka, Ulrike Binder, Mónika Homa, Csaba Vágvölgyi, Ashraf S. Ibrahim, Gábor Nagy, Tamás Papp
Abstract
and identify the mechanism by which one of the CotH proteins contributes to the development of a normal fungal cell wall, thereby indicating that this family of proteins can be targeted for future development of novel therapeutic strategies of mucormycosis.
Topics & Concepts
MucormycosisVirulenceMucorBiologySporeGeneMicrobiologyMortality rateMedicineGeneticsPathologyInternal medicineAspergillusAntifungal resistance and susceptibilityFungal Infections and Studiesbioluminescence and chemiluminescence research