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Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling

Bandarigoda N. Somatilaka, Sun‐Hee Hwang, Vivek Reddy Palicharla, Kevin A. White, Hemant Badgandi, John M. Shelton, Saikat Mukhopadhyay

2020Developmental Cell46 citationsDOIOpen Access PDF

Topics & Concepts

SmoothenedBiologyAdenylyl cyclaseHedgehogCell biologyHedgehog signaling pathwayGLI2cAMP-dependent pathwayCiliumADCY10Intraflagellar transportSignal transductionGLI3ADCY9RepressorGeneticsTranscription factorMutantGeneHedgehog Signaling Pathway StudiesGenetic and Kidney Cyst DiseasesEpigenetics and DNA Methylation
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