Litcius/Paper detail

Fe(OTf)<sub>3</sub>-catalyzed annulation of α,β-unsaturated ketoxime acetates with enaminones for the synthesis of functionalized 2,4-diarylpyridines

Xing-Mei Hu, Jing Yang, Jia-Ming Yang, Bi−Na Shao, Rong Huang, Sheng‐Jiao Yan

2023Organic Chemistry Frontiers16 citationsDOI

Abstract

This method involves a cascade reaction utilizing 1 and enamines 2 as substrates, which occurred by refluxing a mixture of the starting materials in toluene with the catalyst Fe(OTf) 3 .

Topics & Concepts

ChemistryAnnulationTolueneCatalysisCascadeOrganic chemistryCombinatorial chemistryMedicinal chemistryChromatographySynthesis and Catalytic ReactionsSynthesis of β-Lactam CompoundsAsymmetric Synthesis and Catalysis