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Bioactive Anti-inflammatory, Antibacterial, Antioxidative Silicon-Based Nanofibrous Dressing Enables Cutaneous Tumor Photothermo-Chemo Therapy and Infection-Induced Wound Healing

Yuewei Xi, Juan Ge, Min Wang, Mi Chen, Wen Niu, Wei Cheng, Yumeng Xue, Cai Lin, Bo Lei

2020ACS Nano348 citationsDOI

Abstract

. Additionally, the PPCP nanofibrous matrix significantly promotes the adhesion and proliferation of normal skin cells and accelerates the cutaneous wound healing in normal mice and bacterial-infected mice by enhancing the early angiogenesis. The PPCP nanofibrous matrix with multifunctional bioactivities provides a competitive strategy for skin tumor and bacterial-infection-induced wound healing.

Topics & Concepts

Wound healingAngiogenesisCurcuminIn vivoPhotothermal therapyRegeneration (biology)Materials scienceCancer researchPharmacologyMedicineNanotechnologyImmunologyBiologyCell biologyBiotechnologyWound Healing and TreatmentsNanoplatforms for cancer theranosticsElectrospun Nanofibers in Biomedical Applications