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Deferoxamine protects cochlear hair cells and hair cell-like HEI-OC1 cells against tert-butyl hydroperoxide-induced ototoxicity

Peiheng Lu, Pengwei Ma, Wei‐Long Wang, Wei Gao, Jiawei Chen, Hao Yuan, Xuerui Ding, Yu-Qiang Lun, Rui Liang, Siyu Li, Zi Wang, Jianing Guo, Hongkai Mei, Lianjun Lu

2024Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease12 citationsDOI

Topics & Concepts

Oxidative stressReactive oxygen speciesHair cellLipid peroxidationApoptosisDeferoxamineChemistryCell biologyOtotoxicityMitochondrial ROSProgrammed cell deathPharmacologyBiochemistryBiologyCochleaAnatomyGeneticsCisplatinChemotherapyHearing, Cochlea, Tinnitus, GeneticsCancer-related molecular mechanisms researchNeuroinflammation and Neurodegeneration Mechanisms
Deferoxamine protects cochlear hair cells and hair cell-like HEI-OC1 cells against tert-butyl hydroperoxide-induced ototoxicity | Litcius