Stable π-radical nanoparticles as versatile photosensitizers for effective hypoxia-overcoming photodynamic therapy
Xiao Cui, Guihong Lu, Shengzhi Dong, Shengliang Li, Yafang Xiao, Jinfeng Zhang, Yanhong Liu, Xiangmin Meng, Feng Li, Chun‐Sing Lee
Abstract
˙) generation and in vitro cytotoxicity were observed addressing the most important hurdle for successful PDT in the oxygen-deficient tumor microenvironment. In addition, the radical NPs are also demonstrated to have effective in vivo PDT efficacy, and excellent biosafety.
Topics & Concepts
Photodynamic therapyPhotosensitizerCytotoxicityNanoparticlePhotochemistryCancer researchChemistryBiophysicsNanotechnologyMaterials scienceMedicineBiochemistryBiologyIn vitroOrganic chemistryNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPhotodynamic Therapy Research Studies