Genomic and Phenotypic Evolution of Tigecycline-Resistant Acinetobacter baumannii in Critically Ill Patients
Jian Gang Zhang, Jinru Xie, Henan Li, Zhiren Wang, Yuyao Yin, Shuyi Wang, Hongbin Chen, Qi Wang, Hui Wang
Abstract
, were the key genes related to the virulence of A. baumannii in hosts. Our research provides a theoretical basis for elucidating the mechanism of tigecycline resistance and presents new clues for future surveillance and treatment of multidrug-resistant A. baumannii.
Topics & Concepts
TigecyclineAcinetobacter baumanniiBiologyMicrobiologyVirulenceAntibiotic resistanceGalleria mellonellaBiofilmAntibioticsGeneGeneticsBacteriaPseudomonas aeruginosaAntibiotic Resistance in BacteriaBacterial biofilms and quorum sensingVibrio bacteria research studies