Liquid–liquid phase separation induced by crowding condition affects amyloid-β aggregation mechanism
Ryuki Kobayashi, Hideki Nabika
Abstract
Liquid–liquid phase separation induced by crowding condition affects the localization and fibril formation of amyloid-β.
Topics & Concepts
CrowdingLiquid liquidMechanism (biology)FibrilAmyloid fibrilLiquid phaseAmyloid (mycology)Phase (matter)ChemistryBiophysicsChromatographyAmyloid βMaterials scienceThermodynamicsBiochemistryOrganic chemistryPsychologyNeuroscienceBiologyPhysicsInternal medicineMedicineQuantum mechanicsInorganic chemistryDiseaseRNA Research and SplicingAlzheimer's disease research and treatmentsProtein Structure and Dynamics