Tannin-bridged magnetic responsive multifunctional hydrogel for enhanced wound healing by mechanical stimulation-induced early vascularization
Peng Wang, Caili Lv, Xiaosong Zhou, Zhenxu Wu, Zongliang Wang, Yu Wang, Liqiang Wang, Yongzhan Zhu, Min Guo, Peibiao Zhang
Abstract
study confirmed the anti-inflammatory properties of the TA-CFO/PVA hydrogel. More importantly, the TA-CFO/PVA hydrogel accelerated wound healing under a SMF, which contributed to the early vascularization induced by mechanical stimuli generated from the TA-CFO/PVA nanocomposite hydrogel. As a proof-of-concept, we provided an optimizing strategy for magneto-controlled skin tissue regeneration, which may have important guiding significance for the clinical application of magnetic field-assisted therapy.
Topics & Concepts
Wound healingMaterials scienceStimulationBiomedical engineeringSelf-healingTanninNanotechnologyMedicineChemistrySurgeryPathologyInternal medicineAlternative medicineFood scienceElectrospun Nanofibers in Biomedical ApplicationsWound Healing and TreatmentsHydrogels: synthesis, properties, applications