Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction
Surya Kant Tripathi, Kannan R. R. Rengasamy, Bijesh Kumar Biswal
Topics & Concepts
PlumbaginApoptosisA549 cellReactive oxygen speciesCytochrome cCaspaseCell biologyCancer cellCaspase-9MitochondrionBiologyChemistryIntrinsic apoptosisCaspase 3Cancer researchBiochemistryProgrammed cell deathCancerGeneticsBioactive Compounds and Antitumor AgentsCancer Mechanisms and TherapyCancer therapeutics and mechanisms