Ameliorate effect of pyrroloquinoline quinone against cyclophosphamide-induced nephrotoxicity by activating the Nrf2 pathway and inhibiting the NLRP3 pathway
Xinhui Lin, Fei Yang, Ju Huang, Su Jiang, Yunping Tang, Jianrong Li
Topics & Concepts
NephrotoxicityPyrroloquinoline quinoneChemistryPharmacologyAntioxidantGlutathioneBiochemistryToxicityEnzymeMedicineCofactorOrganic chemistryChemotherapy-induced organ toxicity mitigationMicrobial metabolism and enzyme functionInflammasome and immune disorders