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Engagement in Meaningful Activities Among Older Adults With Disability, Dementia, and Depression

Anna Oh, Siqi Gan, W. John Boscardin, Theresa A. Allison, Deborah E. Barnes, Kenneth E. Covinsky, Alexander K. Smith

2021JAMA Internal Medicine34 citationsDOIOpen Access PDF

Abstract

trials. Among the 21 vaccines, 17 (81.0%) had at least 1 pivotal efficacy trial that used masking, 20 (95.2%) that used an active or placebo comparator group, and 8 (38.1%) approved based on a clinical primary end point; of these, the median vaccine efficacy was 91.9% (IQR, 79.6%-98.0%) (Table Among the 5 vaccines for diseases for which no FDA-approved vaccine existed at time of approval, 4 (80%) used a clinical primary end point.

Topics & Concepts

MedicineDementiaDepression (economics)GerontologyCross-sectional studyPsychiatryAssociation (psychology)Activities of daily livingDiseaseEpistemologyMacroeconomicsEconomicsPhilosophyPathologyGeriatric Care and Nursing HomesHealth disparities and outcomesAging and Gerontology Research