Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations
James Ross, Montserrat Puigdelloses-Vallcorba, Gonzalo Piñero, Nishant Soni, Wes Thomason, John DeSisto, Angelo Angione, Nadejda M. Tsankova, Maria G. Castro, Matthew Schniederjan, Nitin R. Wadhwani, G. Praveen Raju, Peter Morgenstern, Oren J. Becher, Adam L. Green, Alexander M. Tsankov, Dolores Hambardzumyan
Topics & Concepts
BiologyMicrogliaHistoneMonocyteCancer researchMutationImmunologyGeneticsGeneInflammationGlioma Diagnosis and TreatmentNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancer