Heme-Fe<sup>III</sup> Superoxide, Peroxide and Hydroperoxide Thermodynamic Relationships: Fe<sup>III</sup>-O<sub>2</sub><sup>•–</sup> Complex H-Atom Abstraction Reactivity
Hyun Kim, Patrick J. Rogler, Savita K. Sharma, Andrew W. Schaefer, Edward I. Solomon, Kenneth D. Karlin
Abstract
-OOH species being formed via HAT reactivity of the partner ferric heme superoxide complex.
Topics & Concepts
ChemistryProtonationPeroxideRedoxTetrahydrofuranHydrogen peroxideDissociation (chemistry)Medicinal chemistryFerricInorganic chemistryStereochemistryPhotochemistryPhysical chemistryOrganic chemistryIonSolventMetal-Catalyzed Oxygenation MechanismsPorphyrin and Phthalocyanine ChemistryHemoglobin structure and function