Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals
Dapeng Ju, Wei Zhang, Jiawei Yan, Haijiao Zhao, Wei Li, Jiawen Wang, Meimei Liao, Zhancong Xu, Zhiqiang Wang, Guanshen Zhou, Long Mei, Nannan Hou, Shuhua Ying, Tao Cai, She Chen, Xiaowen Xie, Luhua Lai, Chao Tang, Noheon Park, Joseph S. Takahashi, Niu Huang, Xiangbing Qi, Eric Erquan Zhang
Abstract
Mathematical modeling supported that the observed type 0 phase shifts resulted from derepression of E-box clock gene transcription.
Topics & Concepts
Circadian rhythmCircadian clockBiologyReset (finance)Phase (matter)Phase response curveCell biologyNeuroscienceChemistryEconomicsOrganic chemistryFinancial economicsCircadian rhythm and melatoninSpaceflight effects on biology