A comprehensive in vitro exploration into the interaction mechanism of coumarin derivatives with bovine hemoglobin: Spectroscopic and computational methods
Sona Lyndem, Upasana Hazarika, P. Athul, Anindita Bhatta, Vivek Prakash, Anupam Nath Jha, Atanu Singha Roy
Topics & Concepts
ChemistryCircular dichroismHydrogen bondQuenching (fluorescence)FluorophoreFörster resonance energy transferBinding constantFluorescenceDocking (animal)MoleculeHydrophobic effectLigand (biochemistry)Binding siteCrystallographyFluorescence spectroscopyStereochemistryPhotochemistryBiochemistryOrganic chemistryReceptorPhysicsNursingMedicineQuantum mechanicsProtein Interaction Studies and Fluorescence AnalysisDrug Transport and Resistance MechanismsHemoglobin structure and function