IGF2BP1 enhances the stability of SIK2 mRNA through m6A modification to promote non-small cell lung cancer progression
Yan Xu, Xu Li, Yi Kong, Kang Li, Jia Li, Fang Xu, Shuzhi Liang, Bolin Chen
Topics & Concepts
Gene knockdownMessenger RNADownregulation and upregulationN6-MethyladenosineRNACancer researchCell growthBiologyApoptosisMolecular biologyChemistryImmunoprecipitationCell cultureBiochemistryGeneMethyltransferaseGeneticsMethylationRNA modifications and cancerRNA Research and SplicingHippo pathway signaling and YAP/TAZ