Litcius/Paper detail

Moving Forward Fast with FAST-Forward

Philippa Lewis, Adrian Murray Brunt, Charlotte E. Coles, Susan Griffin, Imogen Locke, Tom Roques

2021Clinical Oncology30 citationsDOIOpen Access PDF

Abstract

Hypofractionated radiotherapy for the adjuvant treatment of breast cancer has been standard practice in the UK since 2009. Ten-year follow-up data from START-B have confirmed the efficacy of 40 Gy in 15 fractions, with reduced toxicity when compared with the previous standard of 50 Gy in 25 fractions [1]. The UK FAST-Forward trial began recruiting in 2011 to identify a five-fraction regimen that was non-inferior to the 15-fraction regimen for the prevention of ipsilateral breast cancer relapse and as safe for adverse effects.

Topics & Concepts

MedicineBreast Cancer Treatment StudiesAdvances in Oncology and RadiotherapyLung Cancer Diagnosis and Treatment