Litcius/Paper detail

Deconstructing the Soil Microbiome into Reduced-Complexity Functional Modules

Dan Naylor, Sarah Fansler, Colin Brislawn, William Nelson, Kirsten Hofmockel, Janet Jansson, Ryan McClure

2020mBio44 citationsDOIOpen Access PDF

Abstract

The taxonomic and functional diversity inherent to the soil microbiome complicate assessments of the metabolic potential carried out by the community members. An alternative approach is to break down the soil microbiome into reduced-complexity subsets based on metabolic capacities (functional modules) prior to sequencing and analysis. Here, we demonstrate that this approach successfully identified specific phylogenetic and biochemical traits of the soil microbiome that otherwise remained hidden from a more top-down analysis.

Topics & Concepts

MicrobiomeComputational biologyMetagenomicsBiologyComputer scienceBioinformaticsGeneticsGeneMicrobial Community Ecology and PhysiologySoil Carbon and Nitrogen DynamicsGut microbiota and health