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Design, synthesis and anticancer activity of novel 2-arylbenzimidazole/2-thiopyrimidines and 2-thioquinazolin-4(3H)-ones conjugates as targeted RAF and VEGFR-2 kinases inhibitors

Islam H. Ali, Heba T. Abdel‐Mohsen, Marwa M. Mounier, Mahmoud T. Abo‐Elfadl, Ahmed M. El Kerdawy, Iman A. Y. Ghannam

2022Bioorganic Chemistry55 citationsDOI

Topics & Concepts

ChemistryConjugateKinaseVEGF receptorsPharmacologyBiochemistryCancer researchBiologyMathematicsMathematical analysisSynthesis and biological activityMelanoma and MAPK PathwaysCancer Mechanisms and Therapy
Design, synthesis and anticancer activity of novel 2-arylbenzimidazole/2-thiopyrimidines and 2-thioquinazolin-4(3H)-ones conjugates as targeted RAF and VEGFR-2 kinases inhibitors | Litcius