“UV-Driven Self-Cleaning” Magnetic Molecularly Imprinted Absorbents Coupled with LTP-MS and LC-TQ-MS for Rapid High-Throughput Screening and Quantification of Organophosphorus Pesticides in Agro-products
Jia Lin Wang, Chen Yi Zhang, Xuan Li, Xiaodong Wang, Min Cao, Tadao Asami, Xiao Hui Xiong, Jian Chen, Yi Lu
Abstract
Organophosphorus magnetic molecularly imprinted polymers (OMMIPs) with high adsorption capacities (13.5–83.8 mg g –1 ) and good applicability were developed for efficient extraction and pre-concentration of multiple organophosphorus pesticides (OPPs) from foodstuffs. The OMMIP-based sample pretreatment coupled with low-temperature plasma ambient ionization mass spectrometry achieved rapid screening for 90 kinds of pesticides at default maximum residue limits of National Standard (GB 2763-2021) in nine types of agro-products. The OMMIP-based liquid chromatography coupled with triple quadrupole mass spectroscopy assay demonstrated rapid magneto-actuated isolation, efficient removal of matrix interference, and reduced signal suppression, resulting in a short detection time (30 min), compliant recoveries (60.1–127.5%), low detection limits (0.0001–0.073 μg g –1 ), and simultaneous quantification of multi-pesticides. The yolk–shell-structured OMMIPs (Fe 3 O 4 @mTiO 2 @MIPs) demonstrated additional benefits of excellent ultraviolet light-driven catalytic degradation activity toward OPPs, making them eco-friendly for self-cleaning regeneration and reducing laboratory pesticide discharge. This work highlights the potential of OMMIPs for high-throughput and in situ pesticide monitoring in modern large-scale agricultural markets.