Axial functionalisation of photoactive diazido platinum(<scp>iv</scp>) anticancer complexes
Huayun Shi, Cinzia Imberti, Guy J. Clarkson, Peter J. Sadler
Abstract
> 20 μM). Significantly higher platinum cellular accumulation and photo-generated ROS levels were observed for the di-functionalised complexes compared with their mono-functionalised analogues when cancer cells were treated under the same concentrations.
Topics & Concepts
PlatinumChemistryBiochemistryCatalysisMetal complexes synthesis and propertiesLanthanide and Transition Metal ComplexesPorphyrin and Phthalocyanine Chemistry