PROTACs to address the challenges facing small molecule inhibitors
Pedro Martín-Acosta, Xiangshu Xiao
Topics & Concepts
Drug discoverySmall moleculeAllosteric regulationChemistryUbiquitin ligaseChemical biologyComputational biologyLinkerProtein degradationUbiquitinNanotechnologyBiochemistryBiologyComputer scienceReceptorGeneOperating systemMaterials scienceProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments