Litcius/Paper detail

Circuit Topology Analysis of Polymer Folding Reactions

Maziar Heidari, Helmut Schießel, Alireza Mashaghi

2020ACS Central Science33 citationsDOIOpen Access PDF

Abstract

Circuit topology is emerging as a versatile measure to classify the internal structures of folded linear polymers such as proteins and nucleic acids. The topology framework can be applied to a wide range of problems, most notably molecular folding reactions that are central to biology and molecular engineering. In this Outlook, we discuss the state-of-the art of the technology and elaborate on the opportunities and challenges that lie ahead.

Topics & Concepts

Folding (DSP implementation)Topology (electrical circuits)Computer sciencePolymerRange (aeronautics)NanotechnologyChemistryMaterials scienceEngineeringMechanical engineeringElectrical engineeringComposite materialOrganic chemistryRNA and protein synthesis mechanismsGenomics and Chromatin DynamicsForce Microscopy Techniques and Applications