Targeted potent antimicrobial benzochromene-based analogues: Synthesis, computational studies, and inhibitory effect against 14α-Demethylase and DNA Gyrase
Ahmed M. Fouda, Ahmed Hassan, Essam M. Eliwa, Hany E. A. Ahmed, Al-Anood M. Al-Dies, Abdelsattar M. Omar, Hesham S. Nassar, Ahmed H. Halawa, Naif Aljuhani, Ahmed M. El‐Agrody
Topics & Concepts
DNA gyraseChemistryAntimicrobialLipophilicityStereochemistryDocking (animal)Minimum inhibitory concentrationCombinatorial chemistryAntibacterial activityIn vitroBiochemistryEscherichia coliBacteriaOrganic chemistryMedicineBiologyNursingGeneGeneticsSynthesis and biological activityBioactive Compounds and Antitumor AgentsCancer therapeutics and mechanisms