Reprogramming CBX8-PRC1 function with a positive allosteric modulator
Junghyun L. Suh, Daniel Bsteh, Bryce Hart, Yibo Si, Tyler Weaver, Carina Pribitzer, Roy Lau, Shivani Soni, Heather Ogana, Justin M. Rectenwald, Jacqueline L. Norris, Stephanie H. Cholensky, Cari A. Sagum, Jessica M. Umana, Dongxu Li, Brian Hardy, Mark T. Bedford, Shannon M. Mumenthaler, Heinz‐Josef Lenz, Yong‐Mi Kim, Gang Greg Wang, Ken Pearce, Lindsey I. James, Dmitri Kireev, Catherine A. Musselman, Stephen V. Frye, Oliver Bell
Topics & Concepts
Gene silencingChromatinReprogrammingAllosteric regulationCell biologyBiologyPolycomb-group proteinsPRC2Induced pluripotent stem cellComputational biologyGeneticsHistone H3CellGeneGene expressionRepressorEmbryonic stem cellReceptorEpigenetics and DNA MethylationGenomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research