Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis
Helena M. Schnell, Richard M. Walsh, Shaun Rawson, Mandeep Kaur, Meera K. Bhanu, Geng Tian, Miguel A. Prado, Ángel Guerra-Moreno, João A. Paulo, Steven P. Gygi, Jeroen Roelofs, Daniel Finley, John Hanna
Topics & Concepts
BiogenesisChaperone (clinical)ProteasomeProteolysisSaccharomyces cerevisiaeChemistryProtein structureCell biologyBiophysicsCrystallographyBiochemistryBiologyStereochemistryYeastEnzymeGeneMedicinePathologyUbiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and DiseasePeptidase Inhibition and Analysis