Genomic Epidemiology of CC30 Methicillin-Resistant Staphylococcus aureus Strains from Argentina Reveals Four Major Clades with Distinctive Genetic Features
Sabrina Di Gregorio, María Sol Haim, Jesús Vielma Vallenilla, Victoria Cohen, Lucía Rago, Lucía Gulone, David M. Aanensen, Silvia Argimón, Marta Mollerach
Abstract
The rise in prevalence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is of public health concern. In Argentina, several studies documented a shift in the epidemiology of CA-MRSA since 2009, with clonal complex 30 (CC30) and, in particular, sequence type 30 MRSA SCC mec type IV(ST30-MRSA-IV) replacing other clones both in communities and in hospitals and possibly displaying increased virulence.
Topics & Concepts
Staphylococcus aureusMolecular epidemiologyEpidemiologyCladeVirulenceMultilocus sequence typingMicrobiologyMethicillin-resistant Staphylococcus aureusMedicineVirologyBiologyGenotypeGeneGeneticsPhylogeneticsBacteriaInternal medicineAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensingBacterial Identification and Susceptibility Testing