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Graph convolutional network-based feature selection for high-dimensional and low-sample size data

Can Chen, Scott T. Weiss, Yang‐Yu Liu

2023Bioinformatics40 citationsDOIOpen Access PDF

Abstract

MOTIVATION: Feature selection is a powerful dimension reduction technique which selects a subset of relevant features for model construction. Numerous feature selection methods have been proposed, but most of them fail under the high-dimensional and low-sample size (HDLSS) setting due to the challenge of overfitting. RESULTS: We present a deep learning-based method-GRAph Convolutional nEtwork feature Selector (GRACES)-to select important features for HDLSS data. GRACES exploits latent relations between samples with various overfitting-reducing techniques to iteratively find a set of optimal features which gives rise to the greatest decreases in the optimization loss. We demonstrate that GRACES significantly outperforms other feature selection methods on both synthetic and real-world datasets. AVAILABILITY AND IMPLEMENTATION: The source code is publicly available at https://github.com/canc1993/graces.

Topics & Concepts

Computer scienceFeature selectionGraphSample size determinationFeature (linguistics)Convolutional neural networkArtificial intelligencePattern recognition (psychology)Sample (material)Data miningStatisticsTheoretical computer scienceMathematicsChemistryLinguisticsChromatographyPhilosophyFace and Expression RecognitionMachine Learning and Data ClassificationDomain Adaptation and Few-Shot Learning
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