Litcius/Paper detail

Structural basis of tropifexor as a potent and selective agonist of farnesoid X receptor

Longying Jiang, Desheng Xiao, Yubin Li, Shuyan Dai, Lingzhi Qu, Xiaojuan Chen, Ming Guo, Hudie Wei, Yongheng Chen

2020Biochemical and Biophysical Research Communications23 citationsDOI

Topics & Concepts

Farnesoid X receptorG protein-coupled bile acid receptorChemistryAgonistPartial agonistBile acidReceptorStereochemistryBiochemistryNuclear receptorGeneTranscription factorDrug Transport and Resistance MechanismsLiver Diseases and ImmunityPregnancy and Medication Impact
Structural basis of tropifexor as a potent and selective agonist of farnesoid X receptor | Litcius