Performance and reproducibility assessment across multiple time-domain near-infrared spectroscopy device replicas
Michele Lacerenza, Alessandro Torricelli, Alberto Tosi, Davide Contini, Alberto Dalla Mora, Antonio Pifferi, Franco Zappa, Mauro Buttafava
Abstract
Reproducibility between different replicas of the same device is an important aspect in the biomedical research field. Multiple replicas of a dual-wavelength, single-channel “NIRSBOX” device have been assembled and characterized. In this work, we present their full performance assessment. Characterization is focused on measurement accuracy, reproducibility, and reliability, following well-defined and widely adopted procedures to assess the quality of diffuseoptics instruments. The results of the performance assessment procedures are promising, demonstrating highly reproducible performances over different time-domain near-infrared spectroscopy devices, a feature of paramount importance when it comes to comparing results from different instruments, e.g. in multicenter studies.