Poria cocos polysaccharides alleviate obesity-related adipose tissue insulin resistance via gut microbiota-derived short-chain fatty acids activation of FGF21/PI3K/AKT signaling
Wen-Wen Liu, Luzhe Yu, Quan Chen, Chen Zhang, Lei Wang, Nianjun Yu, Daiyin Peng, Jinmei Ou, Weidong Chen, Yue Zhang, Yanyan Wang
Topics & Concepts
Insulin resistanceAdipose tissueGut floraPI3K/AKT/mTOR pathwayPolysaccharideProtein kinase BObesityFGF21ChemistryBiochemistryBiologyFood scienceSignal transductionEndocrinologyFibroblast growth factorReceptorFibroblast Growth Factor ResearchGut microbiota and healthMetabolism, Diabetes, and Cancer