Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming
Samantha M. Morrissey, Fan Zhang, Chuanlin Ding, Diego E. Montoya–Durango, Xiaoling Hu, Chenghui Yang, Zhen Wang, Yuan Fang, Matthew P. Fox, Huang‐Ge Zhang, Haixun Guo, David Tieri, Maiying Kong, Corey T. Watson, Robert A. Mitchell, Xiang Zhang, Kelly M. McMasters, Jian Huang, Jun Yan
Topics & Concepts
MicrovesiclesReprogrammingBiologyCancer researchGlycolysisMetastasisPhenotypeMicrovesicleMacrophageCell biologyTumor microenvironmentImmunologyCellCancermicroRNAMetabolismIn vitroGeneTumor cellsEndocrinologyBiochemistryGeneticsExtracellular vesicles in diseaseImmune cells in cancerImmunotherapy and Immune Responses